Bronchiectasis in children and vitamin D deficiency: what is primary?

Bronchiectasis in children is a chronic polyetiological pathology, the pathogenesis of which involves complex interaction between host, respiratory pathogens and environmental factors. The potential contribution vitamin D deficiency to development bronchiectasis particular clinical importance, given growing prevalence worldwide significant incidence bronchiectasis, especially among children. Clinical case. article presents case that illustrates child with disorder - D-controlled pathomorphological processes, probably cause dysmorphic disorders not only musculoskeletal system but also bronchi. Genetic analysis helped confirm primacy girls. Prescribed treatment therapeutic doses had positive effect. However, unfortunately, this there were already partially irreversible morphological changes. Conclusions. Children recurrent or bronchopulmonary disease impaired metabolism have higher risk developing bronchiectasis. Determining level D-binding protein (VDBP) genetic VDBP gene polymorphisms can be useful both for verifying diagnosis personalizing such patients. study was conducted accordance principles Declaration Helsinki. Informed consent child’s parents obtained research. No conflict interests declared by authors. Key words: deficiency,